Radar Interference Mitigation for Automated Driving: Exploring Proactive Strategies

Autonomous driving relies on a variety of sensors, especially on radars, which have unique robustness under heavy rain/fog/snow and poor light conditions. With the rapid increase of the amount of radars used on modern vehicles, where most radars operate in the same frequency band, the risk of radar interference becomes a compelling issue. This article analyses automotive radar interference and proposes several new approaches, which combine industrial and academic expertise, toward the path of interference-free autonomous driving

Improved Learning and Memory in Aged Mice Deficient in Amyloid β-Degrading Neutral Endopeptidase

BACKGROUND: Neutral endopeptidase, also known as neprilysin and abbreviated NEP, is considered to be one of the key enzymes in initial human amyloid-beta (Abeta) degradation. The aim of our study was to explore the impact of NEP deficiency on the initial development of dementia-like symptoms in mice. METHODOLOGY/PRINCIPAL FINDINGS: We found that while endogenous Abeta concentrations were elevated in the brains of NEP-knockout mice at all investigated age groups, immunohistochemical analysis using monoclonal antibodies did not detect any Abeta deposits even in old NEP knockout mice. Surprisingly, tests of learning and memory revealed that the ability to learn was not reduced in old NEP-deficient mice but instead had significantly improved, and sustained learning and memory in the aged mice was congruent with improved long-term potentiation (LTP) in brain slices of the hippocampus and lateral amygdala. Our data suggests a beneficial effect of pharmacological inhibition of cerebral NEP on learning and memory in mice due to the accumulation of peptides other than Abeta degradable by NEP. By conducting degradation studies and peptide measurements in the brain of both genotypes, we identified two neuropeptide candidates, glucagon-like peptide 1 and galanin, as first potential candidates to be involved in the improved learning in aged NEP-deficient mice. CONCLUSIONS/SIGNIFICANCE: Thus, the existence of peptides targeted by NEP that improve learning and memory in older individuals may represent a promising avenue for the treatment of neurodegenerative diseases

Correlation between Synthetic Aperture Radar Surface Winds and Deep Water Velocity in the Amundsen Sea, Antarctica

Abstract: The recent observed thinning of the glacier ice shelves in the Amundsen Sea (Antarctica) has been attributed to warm deep currents, possibly induced by along-coast winds in the vicinity of the glacial ice sheet. Here, high resolution maps of wind fields derived from Synthetic Aperture Radar (SAR) data have been studied and correlated with subsurface measurements of the deep water velocities in the Amundsen Sea area. Focus is on periods with low ice coverage in 2010 and 2011. In 2010, which had comparatively low ice coverage, the results indicate a more rapid response to wind forcing in the deep currents than in 2011. The SAR wind speed maps have better spatial resolution than available reanalysis data, and higher maximum correlation was obtained with SAR data than with reanalysis data despite the lower temporal resolution. The maximum correlation was R = 0.71, in a direction that is consistent with wind-driven Ekman theory. This is significantly larger than in previous studies. The larger correlation could be due to the better spatial resolution or the restriction to months with minimum ice coverage. The results indicate that SAR is a useful complement to infer the subsurface variability of the ocean circulation in remote areas in polar oceans. Remote Sens. 2013, 5 408